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化学进展 2012, Vol. Issue (9): 1751-1764 前一篇   后一篇

• 综述与评论 •

基于巯基点击反应与RAFT聚合的功能性聚合物合成

熊兴泉*, 唐忠科, 蔡雷   

  1. 华侨大学材料科学与工程学院 福建省高校功能材料重点实验室 厦门 361021
  • 收稿日期:2012-01-01 修回日期:2012-05-01 出版日期:2012-09-24 发布日期:2012-09-27
  • 通讯作者: 熊兴泉 E-mail:xxqluli@hqu.edu.cn
  • 基金资助:

    国家自然科学基金项目(No.21004024) 、福建省自然科学基金项目(No.2011J01046)、福建省“高校杰出青年科研人才培育计划”(11FJPY02)和中央高校基本科研业务费“福建省杰出青年基金培育计划专项”(JB-SJ1002)资助

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Synthesis of Functional Polymers via Combination of Thiol-Based Click Reactions with RAFT Polymerization

Xiong Xingquan, Tang Zhongke, Cai Lei   

  1. The Key Laboratory for Functional Materials of Fujian Higher Education, College of Materials Science & Engineering, Huaqiao University, Xiamen 361021, China
  • Received:2012-01-01 Revised:2012-05-01 Online:2012-09-24 Published:2012-09-27
可逆加成-裂解链转移聚合(RAFT)由于单体适用面广、聚合条件温和、不受聚合方法的限制等特性, 已经成为活性合成聚合物的有效手段之一。点击化学(click chemistry)由于具有良好的选择性、模块性以及官能团耐受性等特点迅速成为许多研究领域,如药物、聚合物、功能材料等合成的有力工具,同时涌现出了多种基于巯基的点击反应。本文综述了近年来基于巯基的点击反应, 如巯基-烯、巯基-炔、巯基-异氰酸酯、巯基-环氧化物以及巯基-卤代烃等新型点击反应与RAFT聚合相结合在功能性聚合物的制备和修饰中的应用, 相信这两种手段的结合将在其中发挥积极的作用。
关键词： 巯基, 点击反应, RAFT聚合, 功能性聚合物, 修饰
Due to wide range of monomers, mild polymerization conditions and various established polymerization methods, reversible-addition-fragmentation chain transfer (RAFT) polymerization is a useful living polymerization technique for the design and synthesis of polymers. Click chemistry has been demonstrated as a powerful tool in numerous scientific fields including drugs, polymers and functional materials because of its superior selectivity, modularity and functional group tolerance. At the same time, a series of novel thiol-based click reactions thus emerged. Herein, recent tactics that combine thiol-based click reactions, such as thiol-ene, thiol-yne, thiol-icocyanate, thiol-oxirane and thiol-halo with RAFT technique toward the construction and modification of useful functional polymers are reviewed. The combined thiol-based click reaction/RAFT technique is believed to play a positive role in the design and synthesis of functional polymers. Contents 1 Introduction
2 Combination of thiol-based click reactions with RAFT polymerization
2.1 Thiol-ene click chemistry and RAFT polymerization
2.2 Thiol-yne chemistry and RAFT polymerization
2.3 Thiol-icocyanate chemistry and RAFT polymerization
2.4 Thiol-oxirane chemistry and RAFT polymerization
2.5 Thiol-halo chemistry and RAFT polymerization
3 Combination of thiol-disulfide exchange reaction with RAFT polymerization
4 Conclusions and outlook
Key words: thiol group, click chemistry, RAFT polymerization, functional polymers, modification

中图分类号: 

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