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化学进展 2011, Vol. 23 Issue (4): 704-730 前一篇   后一篇

• 综述与评论 •

具有生物活性的植物内生真菌次生代谢产物

朱妍妍, 艾嫦, 张嘉, 张正旺, 赵长琦*   

  1. 北京师范大学生命科学学院 细胞增殖与调控生物学教育部重点实验室 基因工程药物及生物技术北京市重点实验室 北京 100875
  • 收稿日期:2010-10-01 修回日期:2010-11-01 出版日期:2011-04-24 发布日期:2011-02-25
  • 通讯作者: e-mail:zhaochangqi60724@yahoo.com.cn E-mail:zhaochangqi60724@yahoo.com.cn
  • 基金资助:

    十一五国家科技支撑计划(No.2008BAC39B05)和北京师范大学研究生院优秀博士论文培育基金项目(No.08026)资助

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导出 被引次数 ( 31 | 10 )

Bioactive Secondary Metabolites from Endophytic Fungi in Plants

Zhu Yanyan, Ai Chang, Zhang Jia, Zhang Zhengwang, Zhao Changqi*   

  1. Key Lab of Cell Proliferation and Regulation of Biology of Ministry of Education, Beijing Key Lab of Gene Engineering Drugs and Biological Technology, College of Life Science, Beijing Normal University, Beijing 100875, China
  • Received:2010-10-01 Revised:2010-11-01 Online:2011-04-24 Published:2011-02-25

植物内生真菌是指那些在其生活史中的某一段时期生活在植物组织内,对植物组织没有引起明显病害症状的真菌。植物内生真菌几乎在所有植物中存在,它们种类繁多,分布广泛,在长期的自然选择下与寄主植物形成和谐的共生关系,使其产生的次生代谢产物十分丰富,这对农业、医药行业等的发展都具有着巨大的潜在价值。本文对近年来从65种植物中分离获得的74株内生真菌产生的404个次生代谢产物研究进行了分析归纳整理,并对其中194个具有生物学活性的化合物结构和活性进行了综述。

关键词： 生物活性, 内生真菌, 次生代谢产物

The endophytic fungi colonize interior organs of plants, but do not have pathogenic effects on their host(s). They exist in almost all plants and have been recognized as potential sources of novel natural products for exploitation in pharmaceutical and agricultural industries. This review describes about 404 natural products isolated and characterized from over 74 plant-associated fungal strains since 2008, and among them 194 active compounds are elucidated in detail about their structures and biological activities.

Key words: biological activities, endophytic fungi, secondary metabolites

中图分类号: 

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