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化学进展 2011, Vol. 23 Issue (10): 1993-2002   后一篇

• Mini Accounts •

高灵敏共轭聚合物化学传感器

朱春雷, 杨琼, 刘礼兵, 王树*   

  1. 中国科学院化学研究所 北京 100190
  • 收稿日期:2011-05-05 出版日期:2011-10-24 发布日期:2011-09-15
  • 通讯作者: 王树 E-mail:wangshu@iccas.ac.cn
  • 作者简介:Shu Wang was born in 1972 in Cangxian, Hebei Province. He received his B. S. degree from Department of Chemistry, Hebei University in 1994, and Ph.D. degree in organic synthesis at Department of Chemistry, Peking University in 1999. Following two years of postdoctoral research at Institute of Chemistry (1999 –2001), Chinese Academy of Sciences, he moved to Institute of Polymers and Organic Solids, University of California a t Sa nt a Ba r ba r a t o c ont i nue h i s postdoctoral research (2001–2004). In 2004, he became a professor of Institute of Chemist ry, Chinese Academy of Sciences. His current research interests include design, synthesis and properties of light-harvesting conjugated polymers, biosensors and chemical biology.
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Conjugated Polymers for Sensitive Chemical Sensors

Zhu Chunlei, Yang Qiong, Liu Libing, Wang Shu*   

  1. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
  • Received:2011-05-05 Online:2011-10-24 Published:2011-09-15
  • Contact: Wang Shu E-mail:wangshu@iccas.ac.cn

金属离子和化学小分子的检测在人类健康、环境污染以及食品安全等领域具有重要意义，科学工作者们已经在设计、发展高灵敏化学传感器方面进行了大量研究。在过去的几十年里，共轭聚合物由于其卓越的光电性质，引起了人们极大的关注，并取得了众多革命性科技进展。最近，利用共轭聚合物的荧光信号放大机制，人们设计、发展了一系列新型的化学和生物传感体系。共轭聚合物的信号传感机制包括电子转移，荧光共振能量转移以及共轭聚合物聚集或构象改变。本文主要介绍我们实验室在利用共轭聚合物实现金属离子和化学小分子荧光检测方面取得的进展，并对未来发展方向与面临的挑战进行了讨论。

关键词： 共轭聚合物, 信号放大, 金属离子, 化学小分子, 传感器

The detections of metal ion and chemical small molecule are of great importance in view of their influences on human health, environment pollution, and food safety. Thus, considerable researches have been conducted toward designing and developing highly sensitive chemical sensors. In the past few decades, due to the superior electrical properties, conjugated polymers (CPs) have aroused great attentions and numerous revolutionary advances have emerged. More recently, facilitated by their signalamplifying response to sensing events, the possibility of CPs to be used as fluorescent probes toward designing novel chemical and biological sensors have been exploited. This mini account highlights the recent progress of CPs in our group for the detection of metal ion and chemical small molecule based on fluorescence technique. Three different signal transduction mechanisms, including electron transfer, fluorescence resonance energy transfer (FRET) and analyteinduced aggregation or conformational change, are involved in this account and concretely elaborated with corresponding examples. Finally, challenges confronted by CPs and their future directions are discussed.

Contents
1 Introduction
2 CP-based metal ion detection
3 CP-based chemical small molecule detection
4 Conclusions and outlook

Key words: conjugated polymers, signal amplification, metal ions, chemical small molecules, sensors

中图分类号: 

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高灵敏共轭聚合物化学传感器