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化学进展 2010, Vol. 22 Issue (12): 2462-2468 前一篇   

• 综述与评论 •

低温微波技术在化学研究中的应用

童星, 肖小华, 邓建朝, 王家玥, 李攻科   

  1. 中山大学化学与化学工程学院 广州 510275
  • 出版日期:2010-12-24 发布日期:2010-11-04
  • 作者简介:e-mail:cesgkl@mail.sysu.edu.cn
  • 基金资助:

    国家自然科学基金项目(No 20905080, 20375050)、“十一五”国家科技支撑计划重点项目(No.2006BAK03A08)和广东省科技计划项目(No. 2009B010900021)资助

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导出 被引次数 ( 17 )

Applications of Low Temperature Microwave Technique in Chemistry Research

Tong Xing, Xiao Xiaohua, Deng Jianchao, Wang Jiayue, Li Gongke   

  1. School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China
  • Online:2010-12-24 Published:2010-11-04

低温微波技术可用于降低微波反应时体系的温度,减少或消除微波辐射时速热效应带来的副反应,具有快速高效、反应均匀、安全环保等优势,在化学研究中得到了广泛关注和应用。本文介绍了低温微波技术的实现方法,综述了近年来该技术在蛋白质研究、合成反应、天然产物研究和微波化学机理研究等领域中的应用,并展望了低温微波技术的发展方向。

关键词： 低温微波技术, 蛋白质, 催化合成, 天然产物, 微波化学机理

Low temperature microwave technique develops normal microwave heating technique and expanded its application range. The technology can reduce or eliminate the side reaction caused by sever thermal effects. There are several approaches used to achieve low temperature, such as adjusting the microwave radiation source, cooling medium, change of the reactants physical property and controlling the initial temperature of reactants. Low temperature microwave technique is applied widely for its high speed, security, reaction uniformity in chemistry research. By this new technique, some proteins can exposure under microwave radiation without protein denaturation; some catalytic synthesis can achieve higher yield and higher reaction rate than that in normal microwave reaction and some natural products can be extracted under protection from decomposition and oxidization. In addition, this technique can also be used as a tool to research microwave chemical mechanism. In this paper, the low temperature microwave technique is introduced and its application in protein research, catalytic synthesis, natural products research and microwave chemical mechanism research are reviewed. The future development of low temperature microwave technique is prospected.

Contents
1 Introduction
2 Application of LTMT in protein research
2.1 Application of LTMT in protein enzymatic hydrolysis
2.2 Application of LTMT in immunoassay
2.3 Application of LTMT in enzyme linked immunosorbent assay
2.4 Application of LTMT in protein conformation research
3 Application of LTMT in catalytic synthesis
4 Application of LTMT in of natural products research
5 Application of LTMT in microwave chemical mechanism research
6 Prospect of LTMT

Key words: low temperature microwave technology, protein, catalytic synthesis, natural products, microwave chemical mechanism

中图分类号: 

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