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低温微波技术在化学研究中的应用
- 童星, 肖小华, 邓建朝, 王家玥, 李攻科
作者信息
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Applications of Low Temperature Microwave Technique in Chemistry Research
- Tong Xing, Xiao Xiaohua, Deng Jianchao, Wang Jiayue, Li Gongke
Author information
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文章历史
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摘要
低温微波技术可用于降低微波反应时体系的温度,减少或消除微波辐射时速热效应带来的副反应,具有快速高效、反应均匀、安全环保等优势,在化学研究中得到了广泛关注和应用。本文介绍了低温微波技术的实现方法,综述了近年来该技术在蛋白质研究、合成反应、天然产物研究和微波化学机理研究等领域中的应用,并展望了低温微波技术的发展方向。
Abstract
Low temperature microwave technique develops normal microwave heating technique and expanded its application range. The technology can reduce or eliminate the side reaction caused by sever thermal effects. There are several approaches used to achieve low temperature, such as adjusting the microwave radiation source, cooling medium, change of the reactants physical property and controlling the initial temperature of reactants. Low temperature microwave technique is applied widely for its high speed, security, reaction uniformity in chemistry research. By this new technique, some proteins can exposure under microwave radiation without protein denaturation; some catalytic synthesis can achieve higher yield and higher reaction rate than that in normal microwave reaction and some natural products can be extracted under protection from decomposition and oxidization. In addition, this technique can also be used as a tool to research microwave chemical mechanism. In this paper, the low temperature microwave technique is introduced and its application in protein research, catalytic synthesis, natural products research and microwave chemical mechanism research are reviewed. The future development of low temperature microwave technique is prospected.
Contents
1 Introduction
2 Application of LTMT in protein research
2.1 Application of LTMT in protein enzymatic hydrolysis
2.2 Application of LTMT in immunoassay
2.3 Application of LTMT in enzyme linked immunosorbent assay
2.4 Application of LTMT in protein conformation research
3 Application of LTMT in catalytic synthesis
4 Application of LTMT in of natural products research
5 Application of LTMT in microwave chemical mechanism research
6 Prospect of LTMT
关键词
低温微波技术 / 蛋白质 / 催化合成 / 天然产物 / 微波化学机理 {{custom_keyword}} /
Key words
low temperature microwave technology / protein / catalytic synthesis / natural products / microwave chemical mechanism {{custom_keyword}} /
中图分类号：
TN015
TQ025.2
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脚注
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基金
国家自然科学基金项目(No 20905080, 20375050)、“十一五”国家科技支撑计划重点项目(No.2006BAK03A08)和广东省科技计划项目(No. 2009B010900021)资助
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