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化学进展 2010, Vol. 22 Issue (0203): 345-351 前一篇   后一篇

• 综述与评论 •

荧光碳纳米颗粒:新进展和技术挑战*

胡胜亮1,2**;白培康2;孙景3;曹士锐2   

  1. （1. 中北大学仪器科学与动态测度教育部重点实验室 电子测试技术国家重点实验室 太原 030051；2. 中北大学材料科学与工程学院 太原 030051；3. 天津大学材料科学与工程学院 天津 300072）
  • 收稿日期:2009-04-15 修回日期:2009-05-22 出版日期:2010-03-24 发布日期:2010-03-18
  • 通讯作者: 胡胜亮 E-mail:hsliang@yeah.net
  • 基金资助:

    山西省青年科技研究基金;高等学校博士学科点专项科研基金

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Fluorescent Carbon Nanoparticles: Recent Achievements and Technical Challenges

Hu Shengliang1,2**;  Bai Peikang2;  Sun Jing3;  Cao Shirui2   

  1. (1. Key Laboratory of Instrumentation Science & Dynamic Measurement (North University of China), Ministry of Education, National Key Laboratory of Science and Technology on Electronic Test and Measurement, Taiyuan 030051, China; 2. School of Materials Science and Engineering, North University of China, Taiyuan 030051, China; 3. School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China)
  • Received:2009-04-15 Revised:2009-05-22 Online:2010-03-24 Published:2010-03-18
  • Contact: Hu Shengliang E-mail:hsliang@yeah.net

与其它荧光纳米粒子相比，荧光碳纳米颗粒不仅具有良好生物相容性和易于表面功能化等优点，还具有发光稳定并可实现上转换荧光发射的特性，所以在生物医药领域具有重要的应用价值。结合近年来的最新研究成果，本文综述了金刚石、石墨和非晶等不同结构的荧光碳纳米颗粒的制备方法及其局限性；分析了不同结构碳纳米颗粒的荧光发射特性和在生物技术中应用的优缺点；阐述了荧光碳纳米颗粒在今后研究中需要解决的问题和发展方向。

关键词： 荧光, 碳纳米颗粒, 生物相容性, 纳米金刚石

Comparing with other fluorescent nanoparticles (NPs), fluorescent carbon NPs hold not only momentous properties such as good biocompatibility and facile surface functionalizability, but also excellent photostability and up-converting optical property. Therefore, fluorescent carbon NPs have a high potential application in life science and nanomedicine. To summarize the important results of recent studies, this review shows the synthetic methods and its corresponding limitations of fluorescent carbon NPs with different structures including diamond, graphite and non-crystalline, evaluates the fluorescent properties of carbon NPs with different structures, and their merit and challenge in biotechnology application. The important question to research and development directions for fluorescent carbon NPs in the future are described.

Contents
1 Introduction
1.1 Critical questions faced by general fluorescent NPs in life science applications
1.2 Research value of fluorescent carbon NPs
2 Fluorescent carbon NPs with diamond structure
2.1 Doping type
2.2 Surface modification type
3 Fluorescent carbon NPs with other structure
3.1 Fluorescent carbon NPs with graphite structure
3.2 Fluorescent carbon NPs with non-crystalline structure
4 Conclusion and outlook

Key words: fluorescence, carbon nanoparticles, biocompatibility, nanodiamond

中图分类号: 

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