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化学进展 2009, Vol. 21 Issue (6): 1287-1291 前一篇   后一篇

• 综述与评论 •

两步种子溶胀聚合研究进展*

雷金化1,2,王红华1,李栋梁1,2,周光远1**   

  1. (1. 中国科学院长春应用化学研究所   |长春 130022；2. 中国科学院研究生院   |北京 100049)
  • 收稿日期:2008-07-07 修回日期:2008-09-05 出版日期:2009-06-24 发布日期:2009-06-16
  • 通讯作者: 周光远 E-mail:gyzhou@ciac.jl.cn
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Development of Two-Staged Seeded Swelling Polymerization

Lei Jinhua1,2; |Wang Honghua1; |Li Dongliang1,2;   |Zhou Guangyuan1**   

  1. (1.Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China；2.Graduate University of Chinese Academy of Sciences, Beijing 100049, China)
  • Received:2008-07-07 Revised:2008-09-05 Online:2009-06-24 Published:2009-06-16
  • Contact: Zhou Guangyuan E-mail:gyzhou@ciac.jl.cn

由两步种子溶胀聚合法制备的聚合物微球尺寸均一可控，制备的多孔微球孔径、孔分布可控，被广泛应用于色谱柱填料、离子交换树脂、生物分离和催化剂载体等领域。本文介绍了两步种子溶胀聚合的聚合工艺；阐述了两步种子溶胀聚合的溶胀机理以及用该法制备多孔微球的致孔机理；进一步分析了影响两步种子溶胀聚合的各种因素：包括聚合过程的控制以及聚合配方的控制因素等；简要综述了通过该方法所制备的多孔聚合物微球，并对两步种子溶胀聚合方法今后的发展进行了展望。

关键词： 两步种子溶胀, 聚合工艺, 溶胀机理, 致孔机理

Monodisperse micron-sized polymeric particles can be achieved by two-staged seeded polymerization(also known as the activated swelling polymerization). Because of the controllable particles size, pore size and pore size distribution, particles synthesized by this method are widely used as chromatographic supports, ion exchangers, size exclusion chromatography, biological separation, catalytic supports, etc. This paper introduces polymerization process of two-staged seeded swelling polymerization, mechanism of two-staged swelling and pore formation. Then we give a detailed analysis on the impact of two-step seeded swelling polymerization, including control of polymerization process and effect of each component in two-staged seeded swelling polymerization. Preparation of porous polymer microspheres by this method is summarized likewise. Finally, the future trend of two-step seed swelling polymerization is discussed.

Contents
1 Introduction
2 Process of two-staged seeded swelling polymerization
3 Mechanism of two-staged seeded swelling polymerization
3.1 Mechanism of seeded swelling
3.2 Mechanism of pore formation
4 Control of two-staged seeded swelling polymerization
4.1 Control of polymerization process
4.2 Effect of recipe of two-staged seeded polymerization on obtained particles
5 Application of two-staged seeded swelling polymerization
6 Outlook and summary

Key words: two-staged seeded swelling, polymerization process, swelling mechanism, pore formation mechanism

中图分类号: 

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两步种子溶胀聚合研究进展*