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化学进展 2007, Vol. 19 Issue (05): 751-761 前一篇   后一篇

• 综述与评论 •

3-取代吲哚衍生物的合成*

李记太**;代红光;蔺志平   

  1. 河北大学化学与环境科学学院 河北省分析科学技术实验室 保定 071002
  • 收稿日期:2006-06-19 修回日期:2006-07-11 出版日期:2007-05-24 发布日期:2007-05-24
  • 通讯作者: 李记太
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Synthesis of 3-Substituted Indole Derivatives

Li Jitai**;Dai Hongguang;Lin Zhiping   

  1. Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China
  • Received:2006-06-19 Revised:2006-07-11 Online:2007-05-24 Published:2007-05-24
目前吲哚化学的研究是杂环化学中最活跃的领域之一，特别是3-取代吲哚衍生物，已用于许多天然产物和相应具有生物活性化合物重要骨架的构筑，其合成方法的研究格外令人注目。近年来，由吲哚一步合成3-取代吲哚衍生物的报道剧增。本文按合成过程中所用催化剂的种类，综述近几年来由吲哚为原料一步合成二吲哚甲烷、β-吲哚酮、β-吲哚醇、β-吲哚硝基化合物和α-吲哚甲胺等为代表3-取代吲哚衍生物的研究进展。
关键词： 吲哚, 3-取代吲哚, 合成
The research of indoles has been one of the most active areas of heterocyclic chemistry. In particular, 3-substitued indole derivatives have been received much attention as building blocks for the synthesis of many natural products and other biologically active compounds. Recently, there are a lot of reports on the synthesis of 3-substitued indoles from indole. In this article, The one-pot synthesis of 3-substitued indole derivatives from indoles, such as bis (indolyl) methane, β-indolylketone, β-indolylalcohol, β-indolylnitro-compound, α-indolylmethylamine is reviewed according to the kinds of catalysts.
Key words: indole, 3-substitutedindole, synthesis

中图分类号: 

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3-取代吲哚衍生物的合成*