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化学进展 2006, Vol. 18 Issue (01): 114-119 前一篇   后一篇

• 综述与评论 •

多金属氧酸盐抗病毒药物研究*

刘杰1**;王恩波2;计亮年1   

  1. 1.中山大学化学与化学工程学院 广州510275；2. 东北师范大学化学学院 长春130024
  • 收稿日期:2004-12-01 修回日期:2005-03-01 出版日期:2006-01-24 发布日期:2006-01-24
  • 通讯作者: 刘杰
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The Development of Polyoxometalates as Antivirus Drugs

Jie Liu1**;Enbo Wang2;Liangnian Ji1   

  1. 1.School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275,China; 2. Department of Chemistry, Northeast Normal University, Changchun 130024, China
  • Received:2004-12-01 Revised:2005-03-01 Online:2006-01-24 Published:2006-01-24
  • Contact: Jie Liu
多金属氧酸盐在抗病毒、抗肿瘤、抗细菌方面的研究取得了重要进展，本文综述了近30年来多金属氧酸盐在抗艾滋病毒(HIV)、疱疹病毒(HSV-1、HSV-2)、流感病毒等方面的研究情况，详细总结了各种类型多金属氧酸盐的抗病毒效果。结合本课题组的研究结果比较分析了多金属氧酸盐的结构及其抗病毒效果的差异。
关键词： 多金属氧酸盐, 抗病毒药物, 抗病毒机理
The research of antiviral, antitumor and antibacterial properties of polyoxometalates has been well developed recently. In this paper, the development of the research on the inhibitory activities of polyoxometalates against HIV (human immunodeficiency virus), HSV-1 (herpes simplex virus-1), HSV-2 (herpes simplex virus-2) and influenza virus during these 30 years is critically reviewed. The antivirus ability of different kinds of polyoxometalates has also been summarized.
Key words: polyoxometalates, antivirus drugs, antivirus activity

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摘要

多金属氧酸盐抗病毒药物研究*