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化学进展 2005, Vol. 17 Issue (06): 1116-1122 前一篇   

• 综述与评论 •

氧化锆基质HPLC 柱填料研究进展*

敦惠娟1**;赵惠敏1;陈立仁2   

  1. 1.河北师范大学化学学院　石家庄 050016

    2.中国科学院兰州化学物理研究所　兰州 730000

  • 收稿日期:2004-11-01 修回日期:2005-01-01 出版日期:2005-11-24 发布日期:2009-04-02
  • 通讯作者: 敦惠娟
  • 基金资助:

    国家自然科学基金;河北师范大学博士基金 No. 20375045;No.L2004B09

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Modification and Application of Zirconia2Based Packings in HPLC Separations

Dun Huijuan1**;Zhao Huimin1;Chen Liren2   

  1. 1.Department of Chemistry , Hebei Normal University , Shijiazhuang 050016,China;

    2. Lanzhou Institute of Chemical Physics , The Chinese Academy of Sciences,Lanzhou 730000,China

  • Received:2004-11-01 Revised:2005-01-01 Online:2005-11-24 Published:2009-04-02
  • Contact: Dun Huijuan
氧化锆具有很好的化学、机械和热稳定性,适合于碱性物质,特别是生物大分子的分离。氧化锆的色谱性能与硅胶形成很好的互补,具有广阔的应用前景。本文对氧化锆微球表面修饰方法及在色谱分析中的应用进行了综述分析。分析表明氧化锆是性能优异的色谱基质填料。
关键词： 高效液相色谱(HPLC), 色谱填料, 氧化锆
Zirconia exhibits excellent chemical,thermal and mechanical stability. Recently,there has been an increasing importance in application of zirconia support for their good basic and bioanalytic suitability. Zirconia shows different selectivity from silica and it enriches the power of high performance liquid chromatography (HPLC).In this review,the various modifications of zirconia packings,their application in HPLC separations are outlined.It has been found that zirconia is a promising HPLC packing support .
Key words: high performance liquid chromatography (HPLC), packings, zirconia

中图分类号: 

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氧化锆基质HPLC 柱填料研究进展*