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化学进展 2005, Vol. 17 Issue (02): 275-285 前一篇   后一篇

• 综述与评论 •

金属配合物催化氮杂环丙烷化和饱和C —H键氮插入反应*

王　钦1,2 　李　玫1 　余孝其1**　 谢如刚1   

  1. (1 四川大学化学学院　成都610064 ; 2泸州医学院　泸州646000)
  • 收稿日期:2003-12-01 修回日期:2004-06-01 出版日期:2005-03-24 发布日期:2005-03-24
  • 通讯作者: 余孝其 E-mail:schemorg@mail. sc. cninfo. net
  • 基金资助:

    国家自然科学基金

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Progress in Catalytic Aziridination of Alkenes and the Metal2Catalyzed Insertions into Saturated C —H Bonds

Wang Qin1,2 　Li Mei1 　Yu Xiaoqi1**　Xie Rugang1   

  1. (1Department of Chemistry , Sichuan University , Chengdu 610064，China;2Luzhou Medical College , Luzhou 646000 , China)
  • Received:2003-12-01 Revised:2004-06-01 Online:2005-03-24 Published:2005-03-24
  • Contact: Yu Xiaoqi E-mail:schemorg@mail. sc. cninfo. net

氮杂环丙烷是有机合成之砌块,其合成方法是重要的研究课题。本文全面介绍了近20 年来的氮杂环丙烷的金属配合物催化合成,尤其是以氮宾转移到烯烃或碳宾加成到亚胺为合成途径的氮杂环丙烷化催化反应的研究进展,还包括该反应在金属催化时发生的竞争性插入到饱和C —H 键的反应。

关键词： 氮杂环丙烷化, 氮宾, 碳宾, 插入反应

Aziridines are useful building blocks for organic synthesis , which makes them attractive synthetic targets in their own right . This reviewfocuses on aziridine synthesis catalyzed by metal complex during the last twenty years , es2 pecially the progress of the catalytic aziridinations based on nitrene transfer to olefins or on carbene addition to imines. The insertions into saturated C —H bonds , which may compete with metal2catalyzed aziridination , are also included.

Key words: aziridination, nitrene, carbene, insertions

中图分类号: 

()

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