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化学进展 2003, Vol. 15 Issue (01): 67- 前一篇   后一篇

• 综述与评论 •

卵黄蛋白原的分离测定及其在环境内分泌干扰物质筛选中的应用*

周庆祥;江桂斌**   

  1. (中国科学院生态环境研究中心 北京 100085)
  • 收稿日期:2001-12-01 修回日期:2002-09-01 出版日期:2003-01-24 发布日期:2003-01-24
  • 通讯作者: 江桂斌
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Separation and deter mination of vitelllogenin and lts Application as a biomarker for the screening of environmental endocrine disrupting chemicals

Zhou Qingxiang;Jiang Guibin**   

  1. (Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences, Beijing 100085, China)
  • Received:2001-12-01 Revised:2002-09-01 Online:2003-01-24 Published:2003-01-24
  • Contact: Jiang Guibin
环境内分泌干扰物的存在直接威胁野生动物的生存和人类的健康，对其作用机制及筛选方法的研究，已经成为环境科学研究的热点领域。近年来，卵黄蛋白原作为环境内分泌干扰物的“生物标志物”，得到了较深入的研究。本文讨论了卵黄蛋白原的分离测定方法及其在内分泌干扰物筛选中应用的最新进展，为建立更有效的卵黄蛋白分离测定方法及发展新的环境内分泌干扰物筛选技术提供参考。
关键词： 卵黄蛋白, 环境内分泌干扰物质, 生物标志物
Environmental endocrine disruptors have directly threaten on the existing of wildife and health of human beings .The study on the mechanisms and screening methods of which has been the hot topics in screening of environmental endocrine disrupting chemicals .This paper reviewed the advances of separation and mensuration of vitellogenin and its usage in screening environmental endocrine disrupting chemicals in order to offer suggestions for establishing more efficient methods for isolation and measurment ,as well as developing new technology new technology of screening of the environmental endocrine disrupting chemicals .
Key words: vitellogenin, environmental endocrine disrupting chemicals, biomarker

中图分类号: 

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