English
往期目录
新闻公告
More
化学进展 2002, Vol. 14 Issue (04): 263- 前一篇   后一篇

• 综述与评论 •

金属离子对蛋白质的折叠、识别、自组装及功能的影响*

蒋明;沈涛;徐辉碧;刘长林**   

  1. 华中科技大学化学系 武汉 430074
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-07-24 发布日期:2002-07-24
  • 通讯作者: 刘长林
下载PDF ( 4996 ) 引用
导出

The Influences of Metal Ions on Protein Folding, Recognition, Self-Assembly and Biological Functions

Jiang Ming;Shen Tao;Xu Huibi;Liu Changlin**   

  1. Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2002-07-24 Published:2002-07-24
  • Contact: Liu Changlin
金属离子不仅影响金属蛋白的空间结构，还与生物大分子的识别、自组装等性质和生物功能密切相关。在很多蛋白质中，金属离子及其配合物可以诱导周围的肽段折叠成正确的结构，我们将其称为金属结合部位作为模板诱导的结构基序（Template-mediated structural motif,TMSM)。深入研究金属离子在蛋白质-核酸自组装体系中生物大分子交联及聚集体中的作用，对理解生命的无机化学基础具有重要意义。
关键词： 金属离子, TMSM, 折叠, 识别, 自组装
Metal ions and their complexes can exert influences on not only three-dimensional structures of proteins, but also biomacromolecular recognition, self-assembly and functions. The metal ions or their complexes can act as templates that mediate the peptide chains around to fold them into correct structures, which is designated as template-mediated structural motif (TMSM). It is of great significance for the bioinorganic chemists to understand the roles of metal ions in the self-assembly of protein-DNA/RNA and biomacromolcular cross-linking and aggregation states.
Key words: metal ions, TMSM, protein folding, recognition, self-assembly

中图分类号: 

()

[ 1 ] Holm R H, Kennepohl P, Solomon E I. Chem. Rev. ,1996, 96: 2239—2314
[ 2 ] Liu C, Xu H. J. Inorg. Biochem. , 2002, 88: 77—86
[ 3 ] Wain R, Pertinhez T A , Tomlinson E J , et al. J. Biol.Chem. , 2001, 276: 45813—45817
[ 4 ] Kang X, Carey J. Biochemistry, 1999, 38: 15944—15951
[ 5 ] Hamada D, Kuroda Y, Kataoka M , et al. J. Mol. Biol. ,1996, 256: 172—186
[ 6 ] Steensma E, Gordon E, LindaM , et al. J. Biol. Chem. ,2001, 23: 5846—5855
[ 7 ] Furbank S J , Rogers M S, Wilmot C M , et al. Proc.Natl. Acad. Sci. USA , 2001, 98: 12932—12937
[ 8 ] Korall R A , Matthews B W. Curr. Opin. Chem. Biol. ,1999, (3) : 578—583
[ 9 ] Vendovas C, Timinskas A , Siksnys V , et al. Proteins,1994, 20: 279—282
[ 10 ] Lippard S J , Erg J M. Principles of Bioinorganic Chemistry (中译本, 席振锋, 姚光庆, 项斯芬译). 北京: 北京大学出版社, 2000. 120—131
[ 11 ] Chakrabarti P, Pal D. Progress in Biophysics &Molecular Biology, 2001, 76: 1—102
[ 12 ] Berman H M , Westbrook J , Feng Z, et al. Nucleic Acids.Res, 2000, 28: 235—242
[ 13 ] Altona C, Sundaralingam M. J. Am. Chem. Soc. , 1972,94: 8205—8212
[ 14 ] Detar D L F, Luthra N P. J. Am. Chem. Soc. , 1977,99: 1232—1244
[ 15 ] Kostrewa D, Winkler F K. Biochemistry, 1995, 34:683—696
[ 16 ] Schmid B, Ribbe M W , Einsle O , et al. Science, 2002,296: 352—356
[ 17 ] Rees D C, Howard J B. Curr. Opin. Chem. Biol. , 2000,4: 559—566
[ 18 ] Merchant S, Dreyfuss B W. Annu. Rev. Plant Physiol.Plant Mol. Biol. , 1998, 49: 25—51
[ 19 ] Brinen L S, Willett W S, Craik C S, et al. Biochemistry,1998, 49: 25—51
[ 20 ] Derewenda U , Derewenda Z, Dodson E J , et al. Nature,1989, 338: 594—596
[ 21 ] Smith G D, Ciszak E, Magrum L A , et al. Acta Crystallogr. , Sect. D , 2000, 56 : 1541—1548
[ 22 ] Gursky O , Badger J , Li Y, et al. Biophys. J. , 1992, 63:1210—1220
[ 23 ] Bush A I. Curr. Opin. Chem. Biol. , 2000, (4) : 184—191
[ 24 ] Knaus K J , Morillas M , Swietnicki W , et al. Nat. Struct.Biol. , 2001, 8: 770—774
[ 25 ] Lehemann S. Curr. Opin. Chem. Biol. , 2002, 6: 187—192
[ 26 ] Norris G E, Anderson B F, Baker E N. Acta Crystallogr.B, 1991, 47: 998—1004
[ 27 ] Sharma A K, Rajashankar K R, Yadav M P, et al. Acta Crystallogr. D, Biol. Crystallogr. , 1999, 55: 1152—1157
[ 28 ] Anderson B F, Baker H M , Norris G E, et al. Nature,1990, 344: 784—787
[ 29 ] Brinen L S, Willett W S. Craik C S, et al. Biochemistry,1996, 35: 5999—6009
[ 30 ] Nar H, Messerschmidt A , Huber R, et al. FEBS L ett. ,1992, 306: 119—124
[ 31 ] Nar H, Messerschmidt A , Huber R, et al. J. Mol. Biol. ,1991, 221: 765—772
[ 32 ] Parfenyev A N , Salminen A , Halonen P, et al. J. Biol.Chem. , 2001, 276: 24511—24518
[ 33 ] Torres A S, Petri V , Rae T D, et al. J. Biol. Chem. ,2001, 276: 38410—38416
[ 34 ] Vakoufari E, Wilson K S, Petratos K, et al. FEBS L ett. ,1994, 347: 203—206
[ 35 ] Machcaynski M C, Gray H B, Richards J H, et al. J. Inorg. Biochem. , 2002, 88: 375—380
[ 36 ] Rulísek L , Vondrásek J. J. Inorg. Biochem. , 1998, 71:115—127
[ 37 ] Feng Y, Sligar S G, Wand A J , et al. Nat. Struct. Biol. ,1994, 1: 30—35
[ 38 ] Falzone C J , Mayer M R, Whiteman E L , et al. Biochemistry, 1996, 35 : 6519—6526
[ 39 ] Opella S J , DeSilva T M , Veglia G. Curr. Opin. Chem.Biol. , 2002, 6: 217—223
[ 40 ] Paoli M. Progress in Biophysics & Molecular Biology,2001, 76: 103—130
[ 41 ] Hardison R. American Scientist, 1999, 87: 83—93
[ 42 ] Holde K E, Miller K I, Decker H, et al. J. Biol. Chem. ,2001, 276: 15563—15566
[ 43 ] Makarova K S, Grishin N V. J. Mol. Biol. , 1999, 292:11—17
[ 44 ] Lu Y, Berry S M , Pfister T D, et al. Chem. Rev. , 2001,101: 3047—3080
[ 45 ] Lombardi A , Nastri F, Pavone V , et al. Chem. Rev. ,2001, 101: 3165—3189
[ 46 ] Venkatraman J , Shankaramma S C, Balaram P, et al.Chem. Rev. , 2001, 101: 3131—3152
[ 47 ] Weaver R F. Molecular Biology. McGraw Hill Companies, Inc. . Authorized reprinting by China Science Press,2000. 53—57
[ 48 ] Stahl G, McCarty G P, Farabaugh P J. Trends. Biochem.Sci. , 2002, 27: 178—183
[ 49 ] Jason L J , Moore S C, Ausio J , et al. J. Biol. Chem. ,2001, 276: 14597—14601
[ 50 ] Heredia J , Crooks M , Zhu Z, et al. J. Bio l. Chem. ,2001, 276: 8793—8797
[ 51 ] Wimberly B T, Brodersen D E, Clemons W M J r , et al.Nature, 2000, 407: 327—339
[ 52 ] Carter A P, Clemons W M , Brodersen D E, et al. Nature,2000, 407: 340—348
[ 53 ] Ogle J M , Brodersen D E, Clemons W M J r, et al. Science, 2001, 292: 897—902
[ 54 ] Yusupov M M , Yusupova G Z, Baucom A , et al. Science,2001, 292: 883—896
[ 55 ] Nissen P, Hansen J , Ban N , et al. Science, 2000, 289:920—930
[ 56 ] Ban N , Nissen P, Hansen J , et al. Science, 2000, 289:905—920
[ 57 ] Carter A P, Clemons W M J r, Brodersen D E, et al.Scinece, 2001, 291: 498—501
[ 58 ] Agalarov S C, Prasad G S, Funke P M , et al. Science,2000, 288: 107—113
[ 59 ] Cramer P. Curr. Opin. Chem. Biol. , 2002, 12: 89—97
[ 60 ] Cramer P, Bushnell D A , Kornberg R D, et al. Science,2001, 292: 1863—1876
[ 61 ] Cramer P, Bushnell D A , Fu J , et al. Science, 2000, 288:640—649
[ 62 ] Gnatt A L , Cramer P, Fu J , et al. Science, 2001, 292:1876—1882
[ 63 ] Bushnell D A , Cramer P, Kornberg R D, et al. Proc.Natl. Acad. Sci. USA , 2002, 99: 1218—1222
[ 64 ] Hopfner K P, Putnam C D, Tainer J A , et al. Curr.Op in. Stru. Bio l. , 2002, 12: 115—122
[ 65 ] Caruthers J M , McKay D B. Curr. Opin. Stru. Biol. ,2002, 12: 123—133
[ 66 ] Warren A J. Curr. Opin. Stru. Biol. , 2002, 12: 107—114
[ 67 ] Bruner S D, Norman D P G, Verdine G L , et al. Nature,2000, 403: 859—866
[ 68 ] Saenger W , Orth P, Kisker C, et al. Angew. Chem. Int.Ed. , 2000, 39: 2042—2052
[ 69 ] Huffman J L , Brennan R G. Curr. Opin. Chem. Biol. ,2002, 12: 98—106
[ 70 ] Hall T M T. Curr. Opin. Stru. Biol. , 2002, 12: 82—88
[ 71 ] Valentine A M , Ishmael F T, Shier V K, et al. Biochemistry, 2001, 40: 15074—15085
[ 72 ] Kentsis A , Gordon R E, Borden K L B, et al. Proc. Natl.Acad. Sci. USA , 2002, 99: 667—672
[ 73 ] Sun L J , Yim C K, Verdine G L , et al. Biochemistry,2001, 40: 11596—11603
[ 74 ] 张庆硕(Zhang Q S) , 王恩多(Wang E D). 生物化学与生物物理进展(Prog. Biochem. Biophys. ) , 1999, 26: 121—125
[ 75 ] 王锐(Wang R) , 胡晓愚(Hu X Y). 化学进展(Progress in Chemistry) , 1995, 7: 277—286
[ 76 ] Lu Y, Berry S M , Pfister T D, et al. Chem. Rev. , 2001,101: 3047—3080
[ 77 ] Molkentin J D. J. Biol. Chem. , 2000, 275: 38949—38952
[ 78 ] Swaminathan K, Flynn P, Reece R J , et al. Nat. Struct.Biol. , 1997, 4: 751—759
[ 79 ] Cowan J A. Chem. Rev. , 1998, 98: 1067—1087
[ 80 ] Winkler F K, Banner D W , Oefner C, et al. EMBO J. ,1993, 12: 1781—1795
[ 81 ] Jeltsch A , Maschke H, Selent U , et al. Biochemistry,1995, 34: 6239—6246
[ 82 ] Riddihough G. Nature, 1994, 370 (6484) : 78—82
[ 83 ] Vipond I B, Halford S E. Biochemistry, 1995, 34: 1113—1119
[ 84 ] Cao W , Mayer A N , Barany F, et al. Biochemistry, 1995,34: 2276—2283
[ 85 ] Copeland K D, Fitzsimons M P, Houser R P, et al. Biochemistry, 2002, 41: 343—356
[ 86 ] Liu C, Yu S, Li D, et al. Inorg. Chem. , 2002, 41: 913—922
[ 87 ] Pabo C O , Peisach E, Grant R A , et al. Annu. Rev.Biochem. , 2001, 70: 313—340
[ 88 ] Bucciantini M , Giannoni E, Chiti F, et al. Nature, 2002,416: 507—511
[ 89 ] Julien J P. Cell, 2001, 104: 581—591
[ 90 ] Uversky V N , Li J , Fink A L , et al. J. Biol. Chem. ,2001, 276: 44284—44296
[ 91 ] Connolly B A , Eckstein F, Pingoud A , et al. J. Biol.Chem. , 1994, 599: 10760—10763
[ 92 ] Grasby J A , Connolly B A. Biochemistry, 1992, 31:7855—7861
[ 93 ] Horton N C, Newberry K J , Perona J J , et al. Proc. Natl.Acad. Sci. USA , 1998, 95: 13489—13494
[ 94 ] Newman M , Lunnen K, Wilson G, et al. EMBO J. ,1998, 17: 5466—5476
[ 95 ] Viadiu H, Aggarwal A K. Nat. Struct. Biol. , 1998, 5:910—916
[1] 李良春, 郑仁林, 黄毅, 孙荣琴. 多组分自组装小分子水凝胶中的自分类组装[J]. 化学进展, 2023, 35(2): 274-286.
[2] 李立清, 郑明豪, 江丹丹, 曹舒心, 刘昆明, 刘晋彪. 基于邻苯二胺氧化反应的生物分子比色/荧光探针[J]. 化学进展, 2022, 34(8): 1815-1830.
[3] 王萌, 宋贺, 李烨文. 三维自组装蓝相液晶光子晶体[J]. 化学进展, 2022, 34(8): 1734-1747.
[4] 韩冬雪, 金雪, 苗碗根, 焦体峰, 段鹏飞. 超分子组装体激发态手性的响应性[J]. 化学进展, 2022, 34(6): 1252-1262.
[5] 尹航, 李智, 郭晓峰, 冯岸超, 张立群, 汤华燊. RAFT链转移剂的选用原则及通用型RAFT链转移剂[J]. 化学进展, 2022, 34(6): 1298-1307.
[6] 周天瑜, 王彦博, 赵翌琳, 李洪吉, 刘春波, 车广波. 水相识别分子印迹聚合物在样品预处理中的应用[J]. 化学进展, 2022, 34(5): 1124-1135.
[7] 张锦辉, 张晋华, 梁继伟, 顾凯丽, 姚文婧, 李锦祥. 零价铁去除水中(类)金属(含氧)离子技术发展的黄金十年(2011-2021)[J]. 化学进展, 2022, 34(5): 1218-1228.
[8] 李红, 史晓丹, 李洁龄. 肽自组装水凝胶的制备及在生物医学中的应用[J]. 化学进展, 2022, 34(3): 568-579.
[9] 刘玉玲, 胡腾达, 李伊莲, 林洋, Borsali Redouane, 廖英杰. 嵌段共聚物薄膜快速自组装方法[J]. 化学进展, 2022, 34(3): 609-615.
[10] 高耕, 张克宇, 王倩雯, 张利波, 崔丁方, 姚耀春. 金属草酸盐基负极材料——离子电池储能材料的新选择[J]. 化学进展, 2022, 34(2): 434-446.
[11] 赵丹, 王昌涛, 苏磊, 张学记. 荧光纳米材料在病原微生物检测中的应用[J]. 化学进展, 2021, 33(9): 1482-1495.
[12] 傅力, 张怀伟, 叶玮婷, 叶辰, 林正得. 固态电分析化学及其植物研究[J]. 化学进展, 2021, 33(8): 1440-1449.
[13] 谢勇, 韩明杰, 徐钰豪, 熊晨雨, 王日, 夏善红. 荧光内滤效应在环境检测领域的应用[J]. 化学进展, 2021, 33(8): 1450-1460.
[14] 任春平, 聂雯, 冷俊强, 刘振波. 反应型次氯酸荧光探针[J]. 化学进展, 2021, 33(6): 942-957.
[15] 于帅兵, 王召璐, 庞绪良, 王蕾, 李连之, 林英武. 多肽基金属离子传感器[J]. 化学进展, 2021, 33(3): 380-393.