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化学进展 2001, Vol. 13 Issue (05): 368- 前一篇   后一篇

• 综述与评论 •

对DNA具有识别和断裂功能的金属插入剂的研究

宋宇飞;杨频*   

  1. 山西大学分子科学研究所 太原 030006
  • 收稿日期:2000-09-01 修回日期:2000-12-01 出版日期:2001-09-24 发布日期:2001-09-24
  • 通讯作者: 杨频
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Progress of Metallo intercalators with the Function of Recognition and Reaction with DNA

Song Yufei;Yang Pin*   

  1. Institute of Molecular Science, Shanxi University, Taiyuan 030006, China
  • Received:2000-09-01 Revised:2000-12-01 Online:2001-09-24 Published:2001-09-24
  • Contact: Yang Pin
本文详尽介绍了国际上对金属配合物与DNA 以插入方式进行识别和反应的前瞻性的工作,为设计能够与特定序列的DNA 进行识别和反应的金属配合物提供了多种策略。
关键词： 金属插入剂, 光开关, 识别, 断裂
The advanced and creative research on metal complexes, which can recognize and react with DNA by intercalation, has been reviewed. All of these works provide a solid base and diverse strategies to carry out the design of small complexes that can bind and react at specific sequences of DNA.
Key words: metallo in tercalators, light switch, recognition, cleavage

中图分类号: 

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