English
往期目录
新闻公告
More
化学进展 1998, Vol. 10 Issue (04): 451- 前一篇   

• 综述与评论 •

细胞凋亡分析测试方法的研究进展*

慈云祥;张春阳; 冯军   

  1. 北京大学化学与分子工程学院 北京 100871
  • 收稿日期:1997-12-01 修回日期:1998-01-01 出版日期:1998-11-24 发布日期:1998-11-24
下载PDF ( 2822 ) 引用
导出

Progress in the Analytical Methods of Apoptosis

Ci Yunxiang;Zhang Chunyang;Feng Jun   

  1. College of Chemistry &Molecular Engineering,Peking University, Beijing 100871, China
  • Received:1997-12-01 Revised:1998-01-01 Online:1998-11-24 Published:1998-11-24

本文对细胞凋亡的测试方法进行了较全面的综述, 介绍了细胞凋亡的形态学特征和生化特征, 重点评述了细胞凋亡的各种分析测试方法, 包括形态学观察法、琼脂糖凝胶电泳法、流式细胞计数法、原位DNA 标记检测法、anti-ssDNA MAbs 分析和PCR 技术。对细胞凋亡测试方法的发展趋势作了讨论。

关键词： 细胞凋亡, 测试方法

A Review with 82 references is presented on the analytical methods of apoptosis (programmed cell death, PCD). It describes the morphological and biochemical characterization of apoptosis and emphasizes on the analytical methods of apoptosis,including morphological observation , agarosegel electrophoretic analysis, flow cytometry, insitu DNA labelling analysis, anti-ssDNA MA bs and polymerase chain reaction (PCR).The trend of analytical methods of apoptosis is also discussed.

Key words: programmed cell death (PCD), analytical methods

中图分类号: 

()

[1 ] Keer J F R, Wyllie A H, Currie A R, J. Cancer, 1972, 26, 239- 257.
[2 ] Arends M J , Morris R G, Wyllie A H, Am. J. Pathol. , 1990, 136, 593- 598.
[3 ] Kerr J F R, Searle J , Harmon B V , Bishop C J , Pespections on Mammalian Cell Death, Oxford University Press, 1987, 93- 128.
[4 ] Arends M J , Wyllie A H, Int. Rev. Exp. Pathol. , 1991, 32, 223- 254.
[5 ] Trump B F, Goidblatt P J , Stowell R E, Lab. Invest. , 1965, 14, 343- 371.
[6 ] Cohen J J , Duke R C, J. Immunol. , 1984, 132, 38- 42.
[7 ] Wyllie A H, Nature, 1980, 284, 555- 557.
[8 ] Kerr J F R, Winterford C M , Harmon B V , Cancer, 1994, 73, 2013- 2025.
[9 ] Bursh W , Laner B, Tinnermann-Trosiener I, Bartel G et al. , Carcinogensis, 1984, 5, 453- 458.
[10 ] Gouyen M L , Lecoeur H, Dulioust A , Enout M G et al. , J. Imunnol. , 1996, 156, 3509.
[11 ] Macklis R M , Lin J Y, Beresford B, Atchr R W et al. , Radia. Res. , 1992, 130, 220- 226.
[12 ] Takano Y S, Harmon B V , Kerr J F R, J. Pathol. , 1991, 163, 326- 329.
[13 ] Markus M B, Cancer Res. , 1995, 55, 2122- 2128.
[14 ] Kedding T W , Schally A V , Radalovia S, Milovanovic S et al. , Cancer Res. , 1992, 52, 2538-2544.
[15 ] McConkey D J , Hartzell P, Duddy S K, Hakansson H, Orrenius S, Science, 1988, 242, 256- 259.
[16 ] Vaux D L , Cory S, Adam J M , Nature, 1988, 335, 440- 442.
[17 ] Hochenbery D, Nanez G, Milliman C, Schreiber R D et al. , Nature, 1990, 348, 334- 336.
[18 ] Yonssh-Ronach E, Resuitzky D, Lottm J , Sachs L et al. , Nature, 1991, 325, 345- 347.
[19 ] 姜泊, 张亚力, 周殿元, 分子生物学常用实验方法, 人民军医出版社, 北京, 1996, 173- 174.
[20 ] Zhang X W , Niu X L , Guo Z G, Acta Biol. Immunol. Sinica, 1997, 17, 47- 51.
[21 ] Douglas J E E, Angela H, Diane J H, Christos P, Cancer Res. , 1996, 56, 2273- 2276.
[22 ] Coligan J , Current Protocolsin Immunology , John Wiley and Sons, New York, 1995.
[23 ] Steven J C, Edwardine N , Ralph R W , Jose Q , Cancer Res. , 1996, 56, 2711- 2714 .
[24 ] Ellen S P, Christian J , Fawn D W , Cary R P et al. , Cancer Res. , 1996, 56, 2745- 2747.
[25 ] He Q Y, Zhang H Q , Pang D B, Chi X S et al. , Acta Phamacol. Sin. , 1996, 17, 545- 549.
[26 ] Matsubara K, Kabota M , Adachis et al. , Exp. Cell Res. , 1994, 210, 19.
[27 ] Emand S A , Gerald L , J. Biol. Chem. , 1990, 265, 17323- 17333.
[28 ] Comton M M , Poultry Sci. , 1991, 70, 521- 529.
[29 ] Masters J N , Finch C E, Sapolshy R M , Endocrinology , 1989, 124, 3083- 3086.
[30 ] Facchinetti A , Tessarollo L , Mazzocchi M , Kingsfon R et al. , J. Immunol. Meth. , 1991, 136,125- 131.
[31 ] Tilly J L , J. Cell Physiol. , 1993, 154, 519.
[32 ] Peng H, William P, Anal. Biochem. , 1992, 207, 163- 165.
[33 ] McConkey D J , Hartzell P, Orrenins S, Arch. Biochem. Biophys. , 1990, 278, 284- 287.
[34 ] Maellaro E, DelB B, Comporti M , Exp. Cell Res. , 1996, 226, 105- 113.
[35 ] Laborea C, Paigen K, Anal. Biochem. , 1980, 102, 344- 352.
[36 ] Dyfed L E, Caroline D, Cancer Res. , 1993, 53, 2133- 2139.
[37 ] VenilN S, Cancer Res. , 1995, 55, 2507- 2510.
[38 ] Harald H J , J. Immunol. , 1995, 154, 3697.
[39 ] Torge D E, Joseph J , Ying H, Michael M , Anal. Biochem. , 1996, 242, 187- 196.
[40 ] Sun D Y, Jing S, Zheng L M , Ujcius D M , Young J D E, J. Exp. Med. , 1994, 179, 559- 568.
[41 ] Ucher D S, Obermiller P S, Eckhart W , Apgar J R et al. , Mol. Cell Biol. , 1992, 12, 3060- 3069.
[42 ] Ormerod M G, Neili C F, Robertson D, Harrap K R, Exp. Cell Res. , 1994, 211, 231- 237.
[43 ] Brown D G, Sun X M , Cohen G M , J. Biol. Chem. , 1993, 268, 3037- 3039.
[44 ] Waller P R, Kokileva L , LeBlanc J , Sikorska M , Bio. Technique, 1993, 15, 1032- 1040.
[45 ] Junxuan L , Mark R K, Chery J , Gretchen G et al. , Anal. Chem. , 1996, 235, 227- 233.
[46 ] Eunhee P, Cosmas I K, Tam T M , Cathering L W et al. , Exp. Cell Res. , 1996, 226, 1- 10.
[47 ] Compton M M , Haskill J S, Gidlowski J A , Endocrinology , 1988, 122, 2158- 2164.
[48 ] Schmid I, Uittenbogaart C H, Keld B, Giorgi J V , J. Immunol. Meth. , 1994, 170, 145.
[49 ] MichelA H, Frank T , Zbigniew D, Exp. Cell Res. , 1992, 201, 184- 191.
[50 ] Herve L , Marie L G, J. Immunol. Meth. , 1996, 198, 87- 99.
[51 ] Pett P X, Lewur H, Zorn E, Dauguet C, J. Cell Biol. , 1995, 130, 157.
[52 ] Ellwart J W , Dormer P, Cytometry , 1990, 11, 239.
[53 ] Belloc F, Dumain P, Boisseaa M R, Jilloustre C et al. , Cytometry , 1994, 17, 59.
[54 ] Suzanna R, Richard C, Charlea S, J. Immunol. Meth. , 1996, 192, 43- 54.
[55 ] Huschescha I I, Jeitner T M , Auersson A W et al. , Exp. Cell Res. , 1994, 212, 161.
[56 ] He Q Y, Zhang H Q , Pang D B, Chi X S et al. , Acta Phamacol. Sin. , 1996, 17, 545- 549.
[57 ] Jan H W , Richard R J , Rob K, Cornelis J H et al. , J. Histochem. Cytochem. , 1993, 41, 7- 12.
[58 ] Suneel M , Amna I, Vilasini S, Sherry D et al. , J. Histochem. Cytochem. , 1994, 42, 1533- 1537.
[59 ] Gold R, Schmied M , Rothe G, Zischier H et al. , J. Histochem. Cytochem. , 1993, 41, 1023- 1030.
[60 ] Li Z, Chen W , Laszlo G R, Richard G M , J. Immunol. Meth. , 1995, 181, 17- 27.
[61 ] Rich H, Hugh L , David H, Roderick D, Cancer Res. , 1996, 56, 4307- 4310.
[62 ] Solomon M , Jason W , Exp. Cell Res. , 1996, 225, 357- 365.
[63 ] Gold R, Lab. Invest. , 1994, 71, 219.
[64 ] Oskar S F, James A R, Everett V S, Luis V , Exp. Cell Res. , 1996, 226, 387- 397.
[65 ] Frankfart O S, Anticancer Res. , 1994, 14, 1861- 1870.
[66 ] Frankfart O S, Seckinger D, Sugarbaker E V , Int. J. Cancer, 1994, 59, 217- 224.
[67 ] Desjardins L M , MacManas J P, Exp. Cell Res. , 1995, 216, 380- 387.
[68 ] Frankfurt O S, Robe J A , Sugarbaker E V , Villa L , Anticancer Res. , 1996, 16 (4A ) , 1979- 19881
[69 ] BediA , Pasricha P J , Akhtar A J , Baker J P et al. , Cancer Res. , 1995, 55, 1811- 1816.
[70 ] Annette J H, Christopher A S, Leslie C S, Victoria E A et al. , Eur. J. Biochem. , 1996, 236,1- 26.
[71 ] Shinji T , Jack R W , Cancer Res. , 1996, 56, 3391- 3394.
[72 ] Candelaria G M , Juan F, Athanassios P K, Peter A S, Cancer Res. , 1996, 56, 694- 699.
[73 ] Arturo S, Ida C, Luigi G, Tersa B et al. , Cancer Res. , 1996, 56, 1991- 1996.
[74 ] Jun-ichi H, Shinji K, Watara K, Shigeomi S et al. , Cancer Res. , 1996, 56, 1713- 1718.
[75 ] Eri J B, Ganry K, Adrienne D C, Said M S et al. , Cancer Res. , 1996, 56, 1727- 1730.
[76 ] Jacobson M D, Fburne J , Raff M C, EM BO J. , 1994, 13, 1899.
[77 ] Osmak M , Eljuga D, Res. Exp. Med. , 1993, 193, 389.
[78 ] Fesus I, Thomazy V , Autuori F et al. , FEB S Lett. , 1989, 245, 150.
[79 ] Gentile V , Thomazy V , Piacentini M et al. , J. Cell Biol. , 1992, 119, 463- 473.
[80 ] Cohen J J , DuKe R C, J. Immunol. , 1984, 132, 38- 42.
[81 ] Milian K M , Mikkelsem S R, Anal. Chem. , 1993, 65, 2317- 2323.
[82 ] Hashimoto K, Ito K, Ishimor Y, Anal. Chem. , 1994, 66, 3830- 3833.
[1] 蒋革, 罗锋, 徐耀忠, 张晓辉. 近紫外光辅助4-硫脱氧胸苷抗癌作用的研究[J]. 化学进展, 2016, 28(8): 1224-1237.
[2] 张小年, 刘亚楠, 杨晓新, 刘杰. 钌配合物诱导肿瘤细胞凋亡的信号通路及其作用机制[J]. 化学进展, 2011, 23(5): 983-990.
[3] 范健,张华林,谭春燕,蒋宇扬. 以肿瘤凋亡相关蛋白和基因为靶的小分子*[J]. 化学进展, 2007, 19(012): 1955-1964.
[4] 徐辉碧,杨祥良,刘琼,王海涛,甘璐. 硒化合物诱导细胞凋亡的信号转导机制[J]. 化学进展, 2002, 14(04): 305-.