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化学进展 2017, Vol. 29 Issue (1): 127-136 DOI: 10.7536/PC160807 前一篇   后一篇

• 综述 •

聚合物Janus微粒材料的制备与应用

翟文中, 何玉凤*, 王斌, 熊玉兵, 宋鹏飞, 王荣民*   

  1. 西北师范大学化学化工学院 生态环境相关高分子材料教育部重点实验室 兰州 730070
  • 收稿日期:2016-08-01 修回日期:2016-11-01 出版日期:2017-01-05 发布日期:2017-01-10
  • 通讯作者: 何玉凤, 王荣民 E-mail:heyuefeng@nwnu.edu.cn;wangrm@nwnu.edu.cn
  • 基金资助:
    国家自然科学基金项目（No.21364012，21263024）资助
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Fabrication and Applications of Polymeric Janus Particles

Wenzhong Zhai, Yufeng He*, Bin Wang, Yubing Xiong, Pengfei Song, Rongmin Wang*   

  1. Key Lab. Eco-Environment-Related Polymer Materials of Ministry of Education, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070, China
  • Received:2016-08-01 Revised:2016-11-01 Online:2017-01-05 Published:2017-01-10
  • Supported by:
    The work was supported by the National Natural Science Foundation of China (No. 21364012, 21263024).
聚合物Janus微粒是指具有各向异性微观结构的微/纳米聚合物粒子。因在乳液稳定、聚合物混合、可控组装、生物医药、多相催化和功能涂层等领域有重要的应用价值，聚合物Janus微粒材料的可控制备和应用研究已成为新型多功能和智能高分子材料研究的前沿领域。本文首先归纳了聚合物Janus微粒在制备方法、环境响应类型和应用领域的最新进展，进而分析了不同制备方法的优缺点。表面选择性修饰、微流体合成技术、自组装和种子聚合等方法都可用于制备具有可控尺寸、微观结构和表面性质的聚合物Janus微粒，但纳米级微粒微观结构的精确控制和大量合成还存在一定的挑战。环境响应性多组分聚合物Janus微粒在自组装和药物控释方面有其特殊的优势，而简单高效的种子聚合法有望应用于工业生产聚合物Janus固体表面活性剂。预计天然和多功能型聚合物Janus微粒的制备和应用研究将会是未来发展的趋势。
关键词： 智能高分子微球, 多功能聚合物, Janus材料, 各向异性微粒, 可控微观结构
Polymeric Janus micro/nano-particles, which have anisotropic microstructures, can be widely applied in many fields, such as stabilizing emulsions, polymer mixing, controllable self-assembly, bio-medicines, heterogeneous catalysis and functional coatings. Therefore, the research on controlled fabrication and applications of polymeric Janus particles has been paid active attention in region of multifunctional and smart polymer materials. In this review, the progress of polymeric Janus particles in the past few years, such as synthetic strategies, stimulative responsibilities and applications, has been summarized. Their advantages and disadvantages have also been briefly discussed. The polymeric Janus particles with controllable sizes, microstructures and surface properties can be prepared via selective surface modifications, microfluidic synthesis, self-assembly, seed polymerization and other preparation strategies. However, the accurate fabrication and high yield of the particles in nanoscale are still a challenge. Stimulative responsibilities of polymeric Janus particles include pH-responsive property, temperature-responsive property, ion-responsive property, light-responsive property and other stimuli-responsive properties. Stimuli-responsive polymeric Janus particles possessing multicomponent structure have their special advantages in self-assembly and drug delivery. Seed polymerization as a simple and efficient strategy can be applied to prepare polymeric Janus surfactants in industrial production. The fabrication and applications of natural and multifunctional polymeric Janus particles are predicted finally as the development trends in the future.

Contents
1 Introduction
2 Synthesis strategies
2.1 Selective surface modifications
2.2 Microfluidic synthesis
2.3 Self-assembly
2.4 Seed polymerization
2.5 Other preparation strategies
2.6 Macromolecular Janus particles
3 Stimulative responsibilities
3.1 pH-responsive property
3.2 Temperature-responsive property
3.3 Ion-responsive property
3.4 Light-responsive property
3.5 Other stimuli-responsive properties
4 Applications
4.1 Solid surfactants
4.2 Building blocks
4.3 Bio-medicines
4.4 Janus films
4.5 Other applications
5 Conclusion

Key words: smart polymer microspheres, multifunctional polymers, Janus materials, anisotropic particles, controllable microstructures

中图分类号: 

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