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化学进展 2014, Vol. 26 Issue (0203): 403-414 DOI: 10.7536/PC130657 前一篇   后一篇

• 综述与评论 •

纳晶纤维素的功能化及应用

吴伟兵*1, 张磊2   

  1. 1. 南京林业大学 江苏省制浆造纸科学与技术重点实验室 南京 210037;
    2. 南京邮电大学 材料科学与工程学院 南京 210046
  • 收稿日期:2013-06-01 修回日期:2013-10-01 出版日期:2014-02-15 发布日期:2013-12-18
  • 通讯作者: 吴伟兵，e-mail：wbwu@njfu.edu.cn E-mail:wbwu@njfu.edu.cn
  • 基金资助:

    国家自然科学基金项目（No.31200453，61205195），江苏高校优势学科建设工程项目和江苏政府留学奖学金项目资助

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Functionalization and Applications of Nanocrystalline Cellulose

Wu Weibing*1, Zhang Lei2   

  1. 1. Jiangsu Provincial Key Lab of Pulp and Paper Science and Technology, Nanjing Forestry University, Nanjing 210037, China;
    2. School of Materials Science & Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210046, China
  • Received:2013-06-01 Revised:2013-10-01 Online:2014-02-15 Published:2013-12-18
  • Supported by:

    The work was supported by the National Natural Science Foundation of China (No. 31200453, 61205195), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) and Jiangsu Provincial Government Scholarship for Overseas Studies

纳晶纤维素（NCC）是一种由价廉的可再生原料制备得到的棒状纳米材料。NCC表面存在的羟基使其可直接进行化学修饰，也可作为生物模板组装负载无机纳米粒子，这赋予了NCC更多的功能。本文对NCC表面组装负载无机纳米粒子的研究进行了重点归纳。NCC具有独特的尺寸结构，优异的强度性质和物理化学性质，毒性较低，没有明显的环境问题，在众多领域有重要的应用价值。本文全面阐述了NCC在复合增强、绿色催化、光电材料、酶固定化、抗菌和医用材料、生物传感器、荧光探针和药物释放等方面的应用，并对其稳定性、相容性和毒性等实际应用性能进行了相应的探讨。

关键词： 纳晶纤维素, 功能化, 生物医学, 催化, 光电材料

Nanocrystalline cellulose (NCC) is a kind of rod-like nanomaterial obtained from inexpensive renewable biomass. The presence of hydroxyl groups on NCC surface allows it to be further functionalized through chemical modification or deposition of nanoparticles. An introduction of the assembly and deposition of metal element, non-metal element, metal oxide, non-metal oxide, and inorganic salt nanoparticles on NCC is presented in this review. NCC has important application value in many fields owing to the unique structure, exceptional strength and physicochemical properties, biocompatibility and low toxicity. NCC has been widely used as reinforcing agent because of its nanoscale dimensions and outstanding mechanical strength. As a nanoscale biotemplate suitable for the assembly of nanoparticles, NCC has been designed to be high-efficiency composite catalyst. With the characteristics of anisotropy, birefringence and liquid crystallinity, NCC has shown important applications as optical and electronic material. Since NCC is modifiable, biocompatible and biodegradable, this review espically focuses on the applications of NCC in the field of biomedicine, such as enzyme immobilization, antimicrobial and medical materials, biosensors, fluorescent probes and drug delivery. The practical considerations including stability, compatibility and cytotoxicity are also discussed. In the future, NCC still needs to overcome the problems of dispersity, intrinsic hydrophily and manufacturing difficulty to realize industrialization and commercialization.

Contents
1 Introduction
2 Functionalization of NCC
2.1 Covalent modification
2.2 Deposition of nanoparticles on NCC
3 Applications of NCC
3.1 Reinforced composites
3.2 Catalysis
3.3 Optical and electronic materials
3.4 Enzyme immobilization
3.5 Antimicrobial and medical materials
3.6 Biosensors
3.7 Fluorescent probes
3.8 Drug delivery
4 Outlook

Key words: nanocrystalline cellulose, functionalization, biomedicine, catalysis, optical and electronic materials

中图分类号: 

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摘要

纳晶纤维素的功能化及应用