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化学进展 2013, Vol. 25 Issue (06): 1023-1030 DOI: 10.7536/PC121106 前一篇   后一篇

• 综述与评论 •

两性离子聚合物的合成及应用

何晓燕*, 周文瑞, 徐晓君, 杨武*   

  1. 西北师范大学化学化工学院 甘肃省生物电化学与环境分析重点实验室 兰州 730070
  • 收稿日期:2012-11-01 修回日期:2013-01-01 出版日期:2013-06-25 发布日期:2013-05-02
  • 通讯作者: 何晓燕,杨武 E-mail:hexy09@163.com;yangw@nwnu.edu.cn[
  • 基金资助:

    国家自然科学基金地区科学基金项目(No.21164010)和甘肃省自然科学基金项目(No.1107RJZA149)资助

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Preparation and Application of Zwitterionic Polymers

He Xiaoyan*, Zhou Wenrui, Xu Xiaojun, Yang Wu*   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Key Lab of Bioelectrochemistry & Environmental Analysis of Gansu Province, Lanzhou 730070, China
  • Received:2012-11-01 Revised:2013-01-01 Online:2013-06-25 Published:2013-05-02

两性离子聚合物因独特的链结构, 使其具有卓越的化学性能、良好的热稳定性与水化性能, 尤其是具有 “反聚电解质效应溶液行为”这一特点, 近年来引起了广泛关注。因大多数两性离子聚合物链内引入了-OH,-COOH,-SO3H等亲水基团, 使其具有抗蛋白质污染、抗细菌黏附及抗凝血等性能。迄今为止, 人们已合成了很多新型的、功能化的两性离子聚合物并将其应用于石油工业、生物医用材料、药物合成和污水处理等各个领域。本文主要对两性离子聚合物的结构、性质、合成方法、应用、最新研究成果及发展前景等作了简单的概述和分析, 并对它的合成方法和应用作了主要介绍, 以期对两性离子聚合物的研究和发展有所借鉴。

关键词： 两性离子聚合物, 反聚电解质效应, 自由基聚合, 药物释放

Because of their unique pendant-side chain structures, zwitterionic polymers present excellent chemical properties, preferable thermal stability and hydration capacity, especially the anti-polyelectrolyte behavior in solution, have attracted broad attention in the world in recent years. Due to the hydrophilic functional groups such as -OH, -COOH and -SO3H present in the molecular structure, zwitterionic polymers are capable of resisting non-specific protein adsorption,bacterial adhesion and blood coagulation even from undiluted blood plasma and serum.Many novel and functional zwitterionic polymers have been synthesized and attracted a great deal of interest in such fields as petroleum industry, biomedical materials, drug synthesis and sewage treatment. In this review, recent progress in the structure, properties, synthesis methods, applications and developing prospects of zwitterionic polymers are summarized, specifically their synthesis methods and applications. We hope it can be helpful for the research and development of the zwitterionic polymers. Contents
1 Introduction
2 Characteristic and classification of polymers
3 Preparation of zwitterionic polymers
3.1 Copolymerization of one or more monomers
3.2 Functionalization of the polymers
4 Application of zwitterionic polymers
4.1 Application of zwitterionic polymers in the petroleum industry
4.2 Application of zwitterionic polymers in the anti-protein pollution
4.3 Application of zwitterionic polymers in drug controlled release
5 Conclusion and outlook

Key words: zwitterionic polymers, anti-polyelectrolyte behavior, radical polymerization, drug release

中图分类号: 

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摘要

两性离子聚合物的合成及应用