生命科学创新报告新兴研发趋势的数据驱动观点

McKenna Christopher,Arlington Steve
表3 专利授权最多的在研小分子药物靶点
CMR Factbook Year
Target Name
2018 2017 2016
Industry Top 30 Industry Top 30 Industry Top 30
Amyloid beta A4 Protein (Abeta) 32 1 42 6 25 6
Epidermal Growth Factor Receptor 61 1 65 1 26 1
Receptor-Type Tyrosine-Protein Kinase FLT3 (FLT-3) 34 1 33 2 23 1
Retinoic Acid Receptor RXR-gamma 38 6 38 6 24 5
Tumor Necrosis Factor (TNF-alpha) 44 4 46 4 24 1
Tyrosine-Protein Kinase BTK 46 2 40 7 25 7
Tyrosine-Protein Kinase JAK1 (JAK-1) 36 2
Tyrosine-Protein Kinase JAK2 (JAK-2) 37 2 31 3
Tyrosine-Protein Kinase JAK3 (JAK-3) 32 1
Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2; KDR) 34 2 35 1 23 2
Bromodomain-Containing Protein 4 (BRD4) 36 7 45 3 23 3
Phosphoinositide 3-kinase 23 4
mTOP 23 4
Histone deacetylase-1 35 1